Methorfinan [Czech]

Methorfinan [Czech] Brand names, Methorfinan [Czech] Analogs

Methorfinan [Czech] Brand Names Mixture

No information avaliable

Methorfinan [Czech] Chemical_Formula

C₁₇H₂₃NO

Methorfinan [Czech] RX_link

http://www.rxlist.com/cgi/generic2/levorphanol.htm

Methorfinan [Czech] fda sheet

Methorfinan [Czech] msds (material safety sheet)

Methorfinan_[Czech] MSDS

Methorfinan [Czech] Synthesis Reference

Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.

Methorfinan [Czech] Molecular Weight

257.371 g/mol

Methorfinan [Czech] Melting Point

198-199 ^oC

Methorfinan [Czech] H₂O Solubility

1840 mg/L

Methorfinan [Czech] State

Solid

Methorfinan [Czech] LogP

3.986

Methorfinan [Czech] Dosage Forms

Tablet

Methorfinan [Czech] Indication

For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate

Methorfinan [Czech] Pharmacology

Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.

Methorfinan [Czech] Absorption

Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.

Methorfinan [Czech] side effects and Toxicity

LD₅₀=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.

Methorfinan [Czech] Patient Information

No information avaliable

Methorfinan [Czech] Organisms Affected

Humans and other mammals